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Literature summary for 2.3.1.5 extracted from

  • Li, P.; Butcher, N.J.; Minchin, R.F.
    Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells role of matrix metalloproteinases and integrin alphaV (2020), Cell Adh. Migr., 14, 1-11 .
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine loss of NAT1 in in MDA-MB-231, HT-29 and HeLa cells increases adherence to collagen but migration of cells is unaffected. NAT1 deletion decreases invasion and induces changes to cell morphology. These effects are independent of matrix metalloproteinases but are related to integrin ITGalphaV expression Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-
HT-29 cell
-
 Homo sapiens
-
MDA-MB-231 cell
-
 Homo sapiens
-

General Information

General Information Comment Organism
physiological function loss of NAT1 in in MDA-MB-231, HT-29 and HeLa cells increases adherence to collagen but migration of cells is unaffected. NAT1 deletion decreases invasion and induces changes to cell morphology. These effects are independent of matrix metalloproteinases but are related to integrin ITGalphaV expression Homo sapiens